Reference Number: JO-2108-474555
Principal Scientist Protein & Biophysics
Rate: Negotiable
Job Type: Permanent
Location: San Diego

Principal Scientist Oncology Protein Engineering
Location: San Diego, California
Salary: Industry leading basic salary
Benefits: Bonus, Stock Options, 401K & more

Novel and unique technology, early discovery and late phase Immuno-Oncology trials, a growing translational and scientific team & cross functional responsibility. These are just a few of the things you can expect when joining this global biotechnology company specialized in targeted cell therapies for precision medicine in Oncology. With a growing presence in the US and recent funding, this organization are currently seeking a Principal Scientist Protein Engineering and Biophysics to report directly into the Chief Scientific Officer.

This role will drive discovery of new therapeutic antibodies and biophysical characterization of proteins as well as protein-protein interactions. It will support the innovation stage as well as development towards the clinical proof of concept of new biologics. Technical experience in protein engineering and molecular biology is required.

Responsibilities will include:
Conduct and design studies in protein engineering to include, protein construction, design, purification, and characterization
Design strategies for antibody discovery using various methods to elicit diverse panels of antibodies
Identify and apply new technologies and workflows
Execute structure-based protein optimization projects (humanization, potency, protein stabilization, pharmacokinetics)
Apply antibody bioinformatics analysis to pipeline and external assets while also applying silico modelling tools to support engineering projects
Serve as the subject matter and scientific expert on multiple projects
Implement new protocols and experimental designs to improve the internal protein engineering platforms
Contribute to novel pipeline candidates including antibodies, proteins & more

PhD or Masters degree
Drug development experience in the industry working on Biologics
Prior Oncology / Cancer Research experience
Biologics & Protein design / construction experience
Hands on experience in DNA construct design
Experience implementing novel anti body discovery platforms
Excellent written and verbal communication skills

The successful candidate will receive an industry leading basic salary with a benefits package to include the likes of a bonus, stock options, 401k, medical benefits & more

Contact/How to learn more:
To find out more information or apply, contact Jacob Burrows via email

CPL Physicians is a specialist US based retained search and contingent staffing firm focusing exclusively on the recruitment of pharmaceutical physicians for pharmaceutical companies, biotechnology firms, Clinical Research Organisations (CROs) and Regulatory Authorities.
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